薛勇彪 XUE Yongbiao
| 专业技术职务： | 研究员 |
|---|---|
| 职 务： | 博士生导师 |
| 电子邮件： | ybxue@big.ac.cn |
| 学科类别： | 分子遗传学 |
1986年，中国科学院发育生物学研究所理学硕士；
1989年，John Innes Institute 和University of East Anglia博士
1990年-1995年，John Innes Centre和University of Oxford博士后
1995年-1997年，John Innes Centre 的Sainsbury Laboratory 任Research Scientist
1995年-2004年，中科院遗传发育所 研究员
2004年-2014年5月，中科院遗传发育所 所长、研究员
2014年5月-2019年11月，中科院北京基因组研究所 所长、研究员
2019年11月-2023年7月，中国科学院北京基因组研究所（国家生物信息中心） 所长、研究员
2023年8月至今 中国科学院北京基因组研究所（国家生物信息中心） 研究员
Research Papers:
1. Yuyun Zhang*, Zijuan Li*, Yu'e Zhang*, Kande Lin*, Yuan Peng, Luhuan Ye, Yili Zhuang, Meiyue Wang, Yilin Xie, Jingyu Guo, Wan Teng, Yiping Tong, Wenli Zhang, Yongbiao Xue, Zhaobo Lang, Yijing Zhang（2021）Evolutionary rewiring of the wheat transcriptional regulatory network by lineage-specific transposable elements, Genome Research, 2021
2. Qi Liu, Zhenglin Du, Sihui Zhu, Wenming Zhao, Hua Chen, Yongbiao Xue, Guoping Zhao13 & Ya-Ping Zhang（2021） Metagenomic evidence for the co-existence of SARS and H1N1 in patients from 2007-2012 flu seasons in France Biosafety and Health, 2021
3. CNCB-NGDC Members and Partners （2021） Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022, Nucleic Acids Research, 2021
4. Chung-I Wu, Haijun Wen, Jian Lu, Xiao-dong Su, Alice C. Hughes, Weiwei Zhai, Chen Chen, Hua Chen, Mingkun Li, Shuhui Song, Zhaohui Qian, Qihui Wang, Bingjie Chen, Zixiao Guo, Yongsen Ruan, Xuemei Lu, Fuwen Wei, Li Jin, Le Kang, Yongbiao Xue, Guoping Zhao13 & Ya-Ping Zhang（2021） On the origin of SARS-CoV-2—The blind watchmaker argument SCIENCE CHINA-LIFE SCIENCES, 2021
5. Shilei Zhao,Tong Sha,Chung-I Wu, Yongbiao Xue,Hua Chen（2021） Will the large-scale vaccination succeed in containing the COVID-19 pandemic and how soon? Quantitative Biology, 2021
6. Qihui Wang, Hua Chen, Yi Shi, Alice C. Hughes, William J. Liu , Jingkun Jiang, George F. Gao, Yongbiao Xue,Yigang Tong（2021） Tracing the origins of SARS-CoV-2: lessons learned from the past, Cell Research, 2021
7. Meiyue Wang ,Zijuan Li ,Yu’e Zhang ,Yuyun Zhang , Yilin Xie ,Luhuan Ye, Yili Zhuang, Kande Lin, Fei Zhao, Jingyu Guo, Wan Teng , Wenli Zhang , Yiping Tong , Yongbiao Xue, Yijing Zhang（2021） An atlas of wheat epigenetic regulatory elements reveals subgenome divergence in the regulation of development and stress responses, THE PLANT CELL, 2021
8. Zhao, Hong; Song, Yanzhai; Li, Junhui; Zhang, Yue; Huang, Huaqiu; Li, Qun; Zhang, Yu'e; Yongbiao Xue（2021） Primary restriction of S-RNase cytotoxicity by a stepwise ubiquitination and degradation pathway in Petunia hybrida The New phytologist, 2021
9. Shuhui Song, Lina Ma, Dong Zou, Dongmei Tian, Cuiping Li, Junwei Zhu, Meili Chen, Anke Wang, Yingke Ma1, Mengwei Li, Xufei Teng, Ying Cui, Guangya Duan, Mochen Zhang, Tong Jin, Chengmin Shi, Zhenglin Du, Yadong Zhang, Chuandong Liu, Rujiao Li, Jingyao Zeng, Lili Hao, Shuai Jiang, Hua Chen, Dali Han, Jingfa Xiao, hang Zhang, Wenming Zhao, Yongbiao Xue, Yiming Bao（2020） The Global Landscape of SARS-CoV-2 Genomes, Variants, and Haplotypes in 2019nCoVR Genomics Proteomics & Bioinformatics, 2020
10. Zheng Gong, Jun-Wei Zhu, Cui-Ping Li, Shuai Jiang, Li-Na Ma, Bi-Xia Tang, Dong Zou, Mei-Li Chen, Yu-Bin Sun, Shu-Hui Song, Zhang Zhang, Jing-Fa Xiao, Yong-biao Xue, Yi-Ming Bao, Zheng-Lin Du, Wen-Ming Zhao（2020） An online coronavirus analysis platform from the National Genomics Data Center Zoological Research,2020, v.41(06):109-112.
11. Xiuxiu Li, Zhuo Chen, Guomin Zhang, Hongwei Lu, Peng Qin, Ming Qi, Ying Yu, Bingke Jiao, Xianfeng Zhao, Qiang Gao, Hao Wang, Yunyu Wu, Juntao Ma, Liyan Zhang, Yongli Wang, Lingwei Deng, Shanguo Yao, Zhukuang Cheng, Diqiu Yu, LihuangZhu, Yongbiao Xue, Chengcai Chu, Aihong Li, Shigui Li & Chengzhi Liang（2020） Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions Science China. Life sciences, 2020
12. CNCB-NGDC Members and Partners,（2020） Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021 Nucleic Acids Research, 2020
13. Wanying Zhao, Xiaolu Qu, Yuhui Zhuang, Ludi Wang, Maurice Bosch, Vernonica E. Franklin-Tong, Yongbiao Xue, Shanjin Huang（2020） Villin controls the formation and enlargement of punctate actin foci in pollen tubes Journal of Cell Science, 2020, 133(6):jcs.237404.
14. Qi Liu, Shilei Zhao, Cheng-Min Shi, Shuhui Song, Sihui Zhu, Yankai Su, Wenming Zhao, Mingkun Li, Yiming Bao, Yongbiao Xue, Hua Chen（2020） Population Genetics of SARS-CoV-2: Disentangling Effects of Sampling Bias and Infection Clusters Genomics Proteomics & Bioinformatics, 2020
15. Wenming Zhao, Shuhui Song, Meili Chen, Dong Zou, Lina Ma, Yingke Ma, Rujiao Li, Lili Hao, Cuiping Li, Dongmei Tian, Bixia Tang, Yanqing Wang, Junwei Zhu, Huanxin Chen, Zhang Zhang, Yongbiao Xue, Yiming Bao（2020） The 2019 novel coronavirus resource Hereditas (Beijing), 2020, 42(2):212-221.
16. Rajesh Yarra, Yongbiao Xue（2020）Ectopic expression of nucleolar DEAD-Box RNA helicase OsTOGR1 confers improved heat stress tolerance in transgenic Chinese cabbage Plant Cell Reports, 2020:1-12
17. Miaomiao Li, Dongfen Zhang, Qiang Gao, Yingfeng Luo, Hui Zhang, Bin Ma, Chunhai Chen, Annabel Whibley, Yu’e Zhang, Yinghao Cao, Qun Li, Han Guo, Junhui Li, Yanzhai Song, Yue Zhang, Lucy Copsey, Yan Li, Xiuxiu Li, Ming Qi, Jiawei Wang, Yan Chen, Dan Wang, Jinyang Zhao, Guocheng Liu, Bin Wu, Lili Yu, Chunyan Xu, Jiang Li, Shancen Zhao, Yijing Zhang, Songnian Hu, Chengzhi Liang, Ye Yin, Enrico Coen and Yongbiao Xue（2019）Genome structure and evolution of Antirrhinum majus L Nature plants doi:10.1038/s41477-018-0349-9
18. Nashaiman Pervaiz, Nazia Shakeel, Ayesha Qasim, Rabail Zehra, Saneela Anwar, Neenish Rana, Yongbiao Xue, Zhang Zhang, Yiming Bao* and Amir Ali Abbasi1* （2019） Evolutionary history of the human multigene families reveals widespread gene duplications throughout the history of animals BMC Evolutionary Biology 19:128 https://doi.org/10.1186/s12862-019-1441-0
19. Members, B.I.G.D.C.（2018） Database Resources of the BIG Data Center in 2019. Nucleic acids research 47, D8-D14
20. Zhaogui Zhang, Baocai Zhang, Zhibin Chen, Dongmei Zhang, Huairen Zhang, Hang Wang, Yu’e Zhang, Darun Cai, Juan Liu, Senlin Xiao, Yanqing Huo, Jie Liu, Lanjun Zhang, Mingming Wang, Xu Liu, Yongbiao Xue, Li Zhao, Yihua Zhou, & Huabang Chen （2018） A PECTIN METHYLESTERASE gene at the maize Ga1 locus confers male function in unilateral cross-incompatibility Nature communications 9,3678
21. Hugo Tavares, Annabel Whibley, David L. Field, Desmond Bradley, Matthew Couchman, Lucy Copsey, Joane Elleouet, Monique Burrus, Christophe Andalo, Miaomiao Li, Qun Li, Yongbiao Xue, Alexandra B. Rebocho, Nicolas H. Barton, & Enrico Coen （2018） Selection and gene flow shape genomic islands that control floral guides. Proceedings of the National Academy of Sciences 115, 11006-11011
22. Bradley, D., Xu, P., Mohorianu, II, Whibley, A., Field, D., Tavares, H., Couchman, M., Copsey, L., Carpenter, R., Li, M., Li, Q., Xue, Y., Dalmay T., Coen E. (2017) Evolution of flower color pattern through selection on regulatory small RNAs. Science 358, 925-928.
23. Li, J., Zhang, Y., Song, Y., Zhang, H., Fan, J., Li, Q., Zhang, D., and Xue, Y.(2017) Electrostatic potentials of the S-locus F-box proteins contribute to the pollen S specificity in self-incompatibility in Petunia hybrida. Plant J 89, 45-57.
24. Zhang, B., Wu,S., Zhang Y., Xu, T., Guo, F., Tang, H., Li, X., Wang, P., Qian, W., Xue Y.,（2016） A High Temperature-Dependent Mitochondrial Lipase EXTRA GLUME1 Promotes Floral Phenotypic Robustness against Temperature Fluctuation in Rice (Oryza sativa L.). PLOS Genetics. doi:10.1371/journal.pgen.1006152
25. Wang, D., Qin, B., Li, X., Tang, D., Zhang, Y., Zheng, Z., Cheng, Z., Xue,Y.,（2016） Nucleolar DEAD-Box RNA Helicase TOGR1 Regulates Thermotolerant Growth as a PrerRNA Chaperone in Rice. PLOS Genetics. doi:10.1371/journal.pgen.1005844
26. Li Q., Zhao T., Yue M., Xue Y., Bao S.,(2016） The Protein Arginine Methylase 5 (PRMT5/SKB1) Gene Is Required for the Maintenance of Root Stem Cells in Response to DNA Damage. JGG 43 (2016) 187e197
27. Liu, W., Fan, J., Li, J., Song, Y., Li,Q., Zhang, Y., Xue, Y., (2014) SCFSLF-mediated cytosolic degradation of S-RNase is required for cross-pollen compatibility in S-RNase-based self-incompatibility in Petuniahybrida. Front.Genet. 5:288 doi: 10.3389/fgene.2014.00228
28. Hu, X., Qian Q., Xu T., Zhang Y., Dong G., Gao, T., Xie, Q., Xue, Y. (2013) The U-Box E3 ubiquitin ligase TUD1 functions with a heterotrimeric G a subunit to regulate brassinosteroid-mediated growth in rice. PLoS Genet 9(3): e1003391
29. Xu, C., Li, M., Wu, J., Guo, H., Li, Q., Zhang, Y., Chai, J., Li, T., Xue, Y. (2013) Identification of a canonical SCFSLF complex involved in S-RNase-based self-incompatibility of Pyrus (Rosaceae). Plant Mol. Biol. 81:245-257
30. Duan,Y. , Xing, Z., Diao, Z., Xu, W., Li, S., Du, X., Wu, G., Wang, C., Lan, T., Meng, Z., Liu, H., Wang, F., Wu, W., Xue, Y. (2012) Characterization of Osmads6-5, a null allele, reveals that OsMADS6 is a critical regulator for early flower development in rice (Oryza sativa L.) . Plant Mol. Biol. 80:429-442
31. Duan, Y., Li, S., Chen, Z., Zheng, L., Diao, Z., Zhou, Y., Lan, T., Guan, H., Pan, R., Xue, Y., Wu, W. (2012). Dwarf and Deformed Flower 1, encoding an F-box protein, is essential for regulating vegetative and floral development in rice (Oryza sativa L.). Plant J. 72:829-842
32. The Tomato Genome Consortium (2012) The tomato genome sequence provides insights into fleshy fruit evolution. Nature 485:635-641
33. Chen, G., Zhang, B., Liu, L., Li, Q., Zhang, Y., Xie, Q., Z., Xue, Y. (2012) Identification of a ubiquitin-binding structure in the S-locus F-box protein controlling S-RNase-based self-incompatibility. J Genet Genom 39:93-102
34. Xu, W., Yang, R., Li, M., Xing, Z., Yang, W., Chen, G., Guo, H., Gong, Z., Du, Z., Zhang, Z., Hu, X., Wang, D., Qian, Q., Wang, T., Su, Z., Xue, Y. (2011) Transcriptome phase distribution analysis reveals diurnal regulated biological processes and key pathways in rice flag leaves and seedling leaves. PLoS One 6: e17613
35. Zhang, Z., Zhang, S., Zhang, Y., Wang, X., Li, D., Li, Q., Yue, M., Li, Q., Zhang, Y., Xu, Y., Xue, Y., Chong, K., Bao, S. (2011) Arabidopsis floral initiator SKB1 confers high salt tolerance by regulating transcription and pre-mRNA splicing through altering histone H4R3 and small nuclear ribonucleoprotein LSM4 methylation. Plant Cell 23:396-411
36. Wei, L., Xu, W., Deng, Z., Su, Z., Xue, Y., Wang, T. (2010) Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa. BMC Genomics 11:338
37. Causier, B., Castillo, R., Xue, Y., Schwarz-Sommer, Z., Davies, B. (2010) Tracing the evolution of the floral homeotic B- and C-function genes through genome synteny. Current Biol. 27:2651-2664
38. Zhao, L., Huang, J., Zhao, Z., Li, Q., Sims, T.L., Xue, Y. (2010) The SKP1-like protein SSK1 is required for cross-pollen compatibility in S-RNase-based self-incompatibility. Plant J. 62:52-63
39. Wang, K., Tang, D., Hong, L., Xu, W., Huang, J., Li, M., Gu, M., Xue, Y., Cheng, Z. (2010) DEP and AFO regulate reproductive habit in rice. PLoS Genet. 6(1): e1000818
40. Liu, F., Xu, W., Wei, Q., Zhang, Z., Tan, L., Chao, D., Yao, D., Wang, C., Yan, H., Sun C. Xue, Y., Su, Z. (2010) Gene expression profiles deciphering rice phenotypic variation between Nipponbare (Japonica) and 93-11(Indica) during oxidative stress. PLoS One 5(1): e8632
41. Li, H., Xue, D., Gao, Z., Yan, M., Xu, W., Xing, Z., Huang, D., Qian, Q., Xue, Y. (2009) A putative lipase gene EXTRA GLUME1 regulates both empty glume fate and spikelet development in rice. Plant J. 57:593-605
42. Zhang, Y., Xu, W., Li, Z., Deng, X., Wu, W., Xue, Y. (2008) F-box protein DOR functions as a novel inhibitory factor for ABA-induced stomatal closure under drought stress in Arabidopsis thaliana. Plant Physiol. 148:2121-2133
43. Xu, S., Deng, Z., Chong, K., Xue, Y., Wang, T. (2008) Dynamic proteomic analysis reveals a switch between central carbon metabolism and alcoholic fermentation in Oryza sativa filling grains. Plant Physiol. 148:908-925
44. Pu, L., Li, Q., Fan, X., Yang, W., Xue, Y. (2008) A R2R3 MYB transcription factor GhMYB109 is required for cotton fiber development. Genetics 180:811-820
45. Chen, J., Ding, J., Ouyang, Y., Du, H., Yang, J., Cheng, K., Zhao, J., Qiu, S., Zhang, X., Yao, J., Liu, K., Wang, L., Xu, C., Li, X., Xue, Y., Xia, M., Ji, Q., Lu, J., Xu. M., Zhang, Q. (2008) A tri-allelic system of S5 is a major regulator of the reproductive barrier and compatibility of indica-japonica hybrids in rice. Proc. Natl. Acad. Sci. USA 105:11436-11441
46. Yang, W., Kong, Z., Omo-Ikerodah, E., Xu, W., Li, Q., Xue, Y. (2008) A calcineurin B-like interacting protein kinase OsCIPK23 functions in pollination and drought stress responses in rice (Oryza sativa L.). JGG 35:531-543
47. Yang, W., Lai, Y., Li, M., Xu, W., Xue, Y. (2008) A novel C2-domain phospholipid binding protein, OsPBP1, is required for pollen fertility in rice. Mol Plant 1:770-785
48. Zhang, D., Yang, Q., Ding, Y., Cao, X., Xue, Y., Cheng, Z. (2008) Cytological characterization of the tandem repetitive sequences and their methylation status in Antirrhinum majus genome. Genomics 92:107-114
49. Liu, F., Xu, W., Tan, L., Xue, Y., Sun, C., Su, Z. (2008) Case study for identification of indel-caused alternative expression isoforms in rice subspecies japonica and indica by integrative genome analysis. Genomics 91:186-194
50. Li, M., Xu, W., Yang, W., Kong, Z., Xue, Y. (2007) Genome-wide gene expression profiling reveals conserved and novel molecular functions of the stigam in rice (Oryza sativa L.). Plant Physiol. 144:1797-1812
51. Yang, Q., Zhang, D., Li, Q., Cheng, Z., Xue, Y. (2007) Heterochromatic and genetic features are consistent with recombination suppression of the self-incompatibility (S)-locus in Antirrhinum. Plant J. 51:140-151
52. Wang, X, Zhang, Y., Ma, Q., Zhang, Z., Xu, Z., Xue, Y., Bao, S., Chong, K. (2007) SKB1-mediated symmetric dimethylation of histone H4R3 controls flowering time in Arabidopsis. EMBO J. 26:1934-1941
53. Dai, S., Chen, T., Chong, K., Xue, Y., Li, S., Wang, T. (2007) Proteomic identification of differentially expressed proteins associated with pollen germination and tube growth reveals characteristics of germinated Oryza sativa pollen. Mol. Cell. Proteomics 6:207-230
54. Kong, Z., Li, M., Yang, W., Xu, W., Xue, Y. (2006) A novel nuclear-localized CCCH-type zinc finger protein, OsDOS, is involved in delaying leaf senescence in rice (Oryza sativa L.). Plant Physiol. 141:1376-1388
55. Huang, J., Zhao, L., Yang, Q., Xue, Y. (2006) AhSSK1, a novel SKP1-like protein that interacts with the S-Locus F-box protein. Plant J. 46:780-793
56. Dai, S., Li, L., Chen, T., Chong, K., Xue, Y., Wang, T. (2006) Proteomic analyses of Oryza sativa mature pollen reveal novel proteins associated potentially with pollen germination and tube growth. Proteomics 6:2504-2529
57. Dong, L., Wang, L., Zhang, Y., Zhang, Y., Deng, X., Xue, Y. (2006) An auxin-inducible F-box protein CEGENDUO negatively regulates auxin-mediated lateral root formation in Arabidopsis. Plant Mol Biol. 60:599-616
58. Lan, L., Li, M., Lai, Y., Xu, W., Kong, Z., Ying, K., Han, B., Xue, Y. (2005) Microarray analysis reveals similarities and variations in genetic programs involved in pollination/fertilization and stress responses in rice (Oryza sativa L.). Plant Mol Biol 59:151-164
59. Wang, Z., Liang, Y., Li, C., Xu, Y., Lan, L., Chen, C., Xu, Z., Xue, Y., Chong, K. (2005) Identification of anther development-related genes by gene expression profiling with a 10-K cDNA microarray in rice (Oryza sativa L.). Plant Mol Biol 58:721-737
60. Causier, B., Castillo, R., Zhou, J., Ingram, R., Xue, Y., Schwarz-Sommer, Z., Davies, B. (2005) Evolution in action：following function in duplicated floral homeotic genes. Curr. Biol. 15:1508-1512
61. Wang, L., Dong, L., Zhang, Y. E., Zhang, Y., Wu, W., Deng, X.W., Xue, Y. (2005) Genome-wide analysis of S-locus F-box –like genes in Arabidopsis thaliana. Plant Mol Biol 56:929-945
62. Qiao, H., Wang, F., Zhao, L., Zhou, J., Lai, Z., Zhang, Y., Robbins, T., Y., Xue, Y. (2004) The F-box protein AhSLF-S2 controls the pollen function of S-RNase-based self-incompatibility. Plant Cell 16:2307-2322
63. Lan, L., Chen, W., Lai, Y., Suo, J., Kong, Z., Li, C., Lu, Y., Zhang, Y., Zhao, X., Zhang, X., Han, B., Cheng, J., Xue, Y. (2004) Monitoring of gene expression profiles and isolation of candidate genes involved in pollination and fertilization in rice (Oryza sativa L.) using a 10K cDNA microarray. Plant Mol Biol 54:471-487
64. Qiao, H., Wang, H., Zhao, L., Zhou, J., Huang, J., Zhang, Y., Xue, Y. (2004) The F-box protein AhSLF-S2 physically interacts with S-RNases that are inhibited by the ubiquitin/26S proteasome pathway of protein degradation during compatible pollination in Antirrhinum.Plant Cell 16:582-295
Reviews and Book Chapters:
1. Chen, G., Zhang, B., Zhao, Z., Sui, Z., Zhang, H., Xue, Y. (2010) “A life or death decision” for pollen tubes in S-RNase-based self-incompatibility. J. Exp. Bot. 61:2027-2037
2. Zhang, Y., Zhao, Z., Xue, Y. (2009) Roles of proteolysis in plant self-incompatibility. Ann. Rev. Plant Biol. 60:21-42
3. Zhang, Q., Li, J., Xue, Y., Han, B., Deng, X. (2008) Rice 2020: A call for an international coordinated effort in rice functional genomics. Mol Plant 1:715-719
4. Li, C., Zhao, J., Jiang, H., Geng, Y., Dai, Y., Fan, H., Zhang, D., Chen, J., Lu, F., Shi, J., Sun, S., Chen, J., Yang, X., Lu, C., Chen, C., Cheng, Z., Ling, H., Wang, Y., Xue, Y., Li, C. (2008) A snapshot of the Chinese SOL Project. JGG 35: 387-390
5. Zhang, Y., Xue, Y. (2008) Molecular biology of S-RNase-based self-incompatibility. Pages 193-215 in Franklin-Tong, V. E. (ed.) Self-Incompatibility in Flowering Plants: Evolution, Diversity and Mechanisms, Springer-Verlag
6. Wang, Y., Xue, Y. and Li, J. (2005) Towards molecular breeding and improvement of rice in China. Trends Plant Sci. 10:610-614
山东农业大学, 北京师范大学，兰州大学和北京大学兼职或客座教授
1996年，中科院王宽诚科研奖；
1998年，国家杰出青年基金；
1994年，国务院政府津贴；
2005年，入选“新世纪百千万人才工程”；
2007年，国家自然科学二等奖
